细胞系知识资源服务#

Cellosaurus MCP Server是一个非官方的模型上下文协议服务器，用于访问SIB Cellosaurus细胞系知识资源，提供细胞系搜索、详细信息获取和数据库版本信息等功能。

---

⚠️ 强制要求：API 密钥#

此 Skill 必须配置 API 密钥才能使用。

• 首次使用时，如果 .env 中没有 XBY_APIKEY， 必须使用 AskUserQuestion 工具向用户询问 API 密钥
• 拿到用户提供的密钥后，调用 scripts.config.set_api_key(api_key) 保存，然后继续处理
• 获取 API 密钥： https://xiaobenyang.com
• 禁止 在缺少 API 密钥时自行搜索或编造数据

---

工作流程（必须遵守）#

你（大模型）是路由层，负责理解用户意图、选择工具、提取参数。代码只负责调用API。

text

用户输入 → 你选择工具 → 提取该工具需要的参数 → 调用 scripts.tools 中的函数 → 返回结果给用户

步骤#

1. 检查 API 密钥：如果 scripts.config.settings.api_key 为空，使用 AskUserQuestion 询问用户，拿到后调用 scripts.config.set_api_key(key) 保存
2. 选择工具：根据用户意图从下方工具列表中选择对应的工具函数
3. 提取参数：根据选中的工具，提取该工具需要的参数
4. 调用工具：使用 关键字参数 调用 scripts.tools 中的函数，例如 scripts.tools.search_schools(score='520', province='北京', category='综合')
5. 返回结果：将工具返回的 raw 数据整理后展示给用户

---

工具选择规则#

根据用户意图选择对应的工具函数：

用户意图工具函数Search for cell lines in the Cellosaurus database.

Use Solr search syntax to find cell lines by various criteria.

Examples#

• Basic name search: "id:HeLa" or "sy:HeLa"
• Species filter: "ox:human" or "ox:9606"
• Disease filter: "di:cancer" or "di:hepatoblastoma"
• Combined: "ox:human di:cancer ca:cancer"
• Site filter: "derived-from-site:liver"

Args: query: Search query using Solr syntax (default: "id:HeLa") fields: List of fields to return (e.g., ["id", "ac", "ox", "di"]) start: Starting index for pagination (default: 0) rows: Number of results to return (default: 10, max: 1000) sort_order: Sort order (e.g., "group asc,derived-from-site desc")

Returns#

text

Dictionary containing search results with cell line information | `scripts.tools.search_cell_lines` |

| Get detailed information about a specific cell line by its accession number.

Args: accession: Cell line accession number (e.g., "CVCL_0030" for HeLa) fields: List of specific fields to return (e.g., ["id", "ac", "str", "di"])

Returns#

text

Dictionary containing detailed cell line information | `scripts.tools.get_cell_line_info` |

| Get information about the current Cellosaurus database release.

Returns#

text

Dictionary containing release version, date, and statistics | `scripts.tools.get_release_info` |

| Find cell lines derived from patients with a specific disease.

Args: disease: Disease name or term (e.g., "hepatoblastoma", "cancer", "leukemia") species: Species filter (default: "human", can be "mouse", "rat", etc.) fields: Specific fields to return limit: Maximum number of results (default: 10)

Returns#

text

Dictionary containing cell lines associated with the disease | `scripts.tools.find_cell_lines_by_disease` |

| Find cell lines derived from a specific tissue or organ.

Args: tissue: Tissue/organ name (e.g., "liver", "lung", "breast", "brain") species: Species filter (default: "human") fields: Specific fields to return limit: Maximum number of results (default: 10)

Returns#

text

Dictionary containing cell lines from the specified tissue | `scripts.tools.find_cell_lines_by_tissue` |

| Get a list of all available fields that can be requested from the Cellosaurus API.

Returns#

text

Dictionary mapping field names to their descriptions | `scripts.tools.list_available_fields` |

如果参数不完整，使用 AskUserQuestion 向用户询问缺失的参数。

---

工具函数说明#

---

scripts.tools.search_cell_lines#

工具描述：Search for cell lines in the Cellosaurus database.

Use Solr search syntax to find cell lines by various criteria.

Examples#

• Basic name search: "id:HeLa" or "sy:HeLa"
• Species filter: "ox:human" or "ox:9606"
• Disease filter: "di:cancer" or "di:hepatoblastoma"
• Combined: "ox:human di:cancer ca:cancer"
• Site filter: "derived-from-site:liver"

Args: query: Search query using Solr syntax (default: "id:HeLa") fields: List of fields to return (e.g., ["id", "ac", "ox", "di"]) start: Starting index for pagination (default: 0) rows: Number of results to return (default: 10, max: 1000) sort_order: Sort order (e.g., "group asc,derived-from-site desc")

Returns#

text

Dictionary containing search results with cell line information

参数定义#

参数名称参数类型是否必填默认值描述querystringfalse"id:HeLa"nullfieldsnullfalsenullstartintegerfalse0.0nullrowsintegerfalse10.0nullsort_ordernullfalsenull

---

scripts.tools.get_cell_line_info#

工具描述：Get detailed information about a specific cell line by its accession number.

Args: accession: Cell line accession number (e.g., "CVCL_0030" for HeLa) fields: List of specific fields to return (e.g., ["id", "ac", "str", "di"])

Returns#

text

Dictionary containing detailed cell line information

参数定义#

参数名称参数类型是否必填默认值描述accessionstringtruenullfieldsnullfalsenull

---

scripts.tools.get_release_info#

工具描述：Get information about the current Cellosaurus database release.

Returns#

text

Dictionary containing release version, date, and statistics

参数定义#

参数名称参数类型是否必填默认值描述

---

scripts.tools.find_cell_lines_by_disease#

工具描述：Find cell lines derived from patients with a specific disease.

Args: disease: Disease name or term (e.g., "hepatoblastoma", "cancer", "leukemia") species: Species filter (default: "human", can be "mouse", "rat", etc.) fields: Specific fields to return limit: Maximum number of results (default: 10)

Returns#

text

Dictionary containing cell lines associated with the disease

参数定义#

参数名称参数类型是否必填默认值描述diseasestringtruenullspeciesstringfalse"human"nullfieldsnullfalsenulllimitintegerfalse10.0null

---

scripts.tools.find_cell_lines_by_tissue#

工具描述：Find cell lines derived from a specific tissue or organ.

Args: tissue: Tissue/organ name (e.g., "liver", "lung", "breast", "brain") species: Species filter (default: "human") fields: Specific fields to return limit: Maximum number of results (default: 10)

Returns#

text

Dictionary containing cell lines from the specified tissue

参数定义#

参数名称参数类型是否必填默认值描述tissuestringtruenullspeciesstringfalse"human"nullfieldsnullfalsenulllimitintegerfalse10.0null

---

scripts.tools.list_available_fields#

工具描述：Get a list of all available fields that can be requested from the Cellosaurus API.

Returns#

text

Dictionary mapping field names to their descriptions

参数定义#

参数名称参数类型是否必填默认值描述

---

---

返回值处理#

工具函数返回 dict 对象：

• result["raw"] - API 原始返回数据（JSON）， 直接将此数据整理后展示给用户
• result["success"] - 是否成功（True/False）
• result["message"] - 状态消息

---

项目结构#

text

xiaobenyang_gaokao_skill/
├── scripts/
│   ├── __init__.py
│   ├── config.py       # 配置管理 + set_api_key()
│   ├── call_api.py      # API 客户端 + call_api()
│   └── tools.py         # 工具函数（直接调用）
├── requirements.txt
└── SKILL.md

---

注意事项#

1. API 密钥是必需的，无密钥时必须通过 AskUserQuestion 询问用户
2. 禁止 在缺少 API 密钥时自行搜索或编造数据